Innovation No. 6 of 77 in the book

The Pregnancy Test

Sprouting grains used to predict pregnancy

When
c. 1300 BCE
Dynasty
18th Dynasty
Era
New Kingdom
See it on a timeline of Egyptian civilization

Around 1300 BCE, a New Kingdom papyrus lays out a pregnancy test: a woman waters two bags of grain, barley and wheat, with her urine for several days. If the grain sprouts, she is pregnant.

The startling part — it half works. When scientists tried it in 1963, the urine of pregnant women really did trigger growth far more often than not, thanks to elevated hormones.

The same test claimed to guess the baby’s sex from which grain grew first. That part is folklore. But the pregnancy detection was real, and it is the first one known.

The world’s first pregnancy test grew in a bag of Egyptian barley.

The recipe survives in hieratic script on Papyrus Berlin 3038, a medical text of the Nineteenth Dynasty, around 1300 BCE, where it sits among other gynaecological treatments. In 1963 Paul Ghalioungui, Sh. Khalil and A. R. Ammar reproduced the method in a laboratory: urine from pregnant women prompted germination in about 70 percent of grain samples, while urine from men and from women who were not pregnant produced no sprouts at all.

Frequently Asked Questions

Why would urine make grain sprout?

The likely trigger is the high concentration of oestrogen in the urine of a pregnant woman, which acts on the seed. That makes the test a working bioassay — reading a hormone through a living organism — thousands of years before hormones were known.

Did the sex-prediction part work?

No. The claim that barley sprouting first meant a boy, and wheat a girl, is folklore and fails under testing. Only the detection of pregnancy itself holds up.